Orlando Jones comes up with a funny question, "Did Yo Mamma tell you? The second game they play is "Tore up from the Floor Up". Cassidy comes through and plays "I'm A Hustla" from his album I'm A Hustla.

They bring people out of the audience that they think look funny and make fun of them. The cast has to go head to head free styling each other and making punch lines. Nick Cannon on the Red Team goes against Christina Millian on the Black Team to see who can win.

, the series puts two teams of comedians against each other in a series of Wild 'n Out games which are all basically "improvisational" comedy games.

The Teams are the "Red Squad", which was the team name until season 5 where they became the "Platinum Squad" and were permanently captained by Cannon; and the "Black Squad", led by a celebrity guest until season 7 where the situation was reversed with Cannon becoming the Black Squad team captain and the celebrity guest leading the Platinum Squad.

In the 2nd round they play a game called "Do Dat Dance". Kevin Hart joins his black team crew in a game called "That's My Dog". The eighth season contains a total of 21 episodes which were broadcast from August 4, 2016 to April 20, 2017 on MTV, marking the first time in almost a decade that the show aired new episodes on its original network.

DJ D-Wrek has to come up with a new dance move and the cast has to create it. In the next game called "Deaf Jam" they have to play out a song without saying any words, and their teammate has to figure it out. In the last game "Wildstyle" everyone pitches in and goes against others. That's where one teammate has to be a dog and the other has to be a person who tries to figure out what the person is saying. The next round DJ D-Wrek explains "The Questions Game" where a Red teammate and a Black teammate have to keep asking questions, and if one teammate doesn't know a question to ask the other team wins the point. In the next game "60 Second Sequel" both of the teams are giving a movie to make a sequel to. In the last round "Wild Style", at the end the black team wins. Method Man comes through, captain of the Black Team.

Upon being revived in 2012, the show was produced in New York City and aired on MTV2 during Seasons 5–7, it also returned to that location for Season 9.

In 2016, the show returned to airing new episodes on MTV and also for the first time since Season 4, production is in Los Angeles.

Each episode also includes a musical performance, occasionally by the guest captain for the Black/Platinum Squad (Nick Cannon performed with Migos in Season 6 in the episode featuring Chanel Iman).

At times, the musical guest comes out just before 'Wild Style' as the judge for the beefs.

For season 8, the colors were revamped once again with the Gold Squad replacing the Black Squad.